论文部分内容阅读
烯丙位碳氢键活化官能化反应是构建碳碳键、碳杂原子键最直接的方法,也是最近有机化学研究的热点之一.从烯丙基底物类型和亲核试剂类型的角度出发,总结了最近几年来钯催化的烯丙位碳氢键活化官能团化反应及其在不对称合成中应用的最新研究进展.同时分析了各种新的钯催化体系在底物兼容性和亲核试剂范围上的优势和不足,并对今后烯丙位碳氢键活化的发展进行了展望.
Alkane carbon-hydrogen bond activation functionalization reaction is the most direct method to construct carbon-carbon bond and carbon hetero-atom bond, which is also one of the hot topics in recent organic chemistry research.From the point of allylic substrate type and nucleophile type, In recent years, palladium-catalyzed allylic carbon-carbon bond activation functionalization reaction and its application in asymmetric synthesis of the latest research progress.At the same time analyzed a variety of new palladium-catalyzed system in the substrate compatibility and the scope of the nucleophile The pros and cons of the carbon-hydrogen bond activation in the future are prospected.