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目的探讨人乳头瘤病毒(human papilloma virus,HPV)筛查对妇女病普查的意义。方法选择1 718例2012年1月—2013年1月进行普查的妇女为研究对象,检查项目包括白带常规检查、液基细胞检查、妇科B超检查、乳腺彩超检查,与此同时,增加HPV筛查,记录并分析筛查结果。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果 1 718例普查者中,52.8%诊断为正常,14.2%诊断为HPV(+),非典型鳞状细胞病变7.2%,阴道炎4.3%,子宫肌瘤7.1%,乳腺疾病13.3%,低度鳞状上皮内病变1.2%。244例HPV(+)者中,30~39岁占39.8%,40~49岁占34.8%,发病率高于其他年龄段。244例HPV(+)者中,HPV阳性同时宫颈液基细胞学检查异常者经阴道镜下活检确诊宫颈上皮内瘤样病变(cervical intraepithelialneoplasia,CIN)16例,其中1例宫颈锥切后病检为原位癌。结论由于HPV阳性与宫颈癌的发生密切相关,早期筛查可助于进一步检查和确诊,早期提供治疗和预防方案,改善HPV阳性者的预后。
Objective To investigate the significance of human papilloma virus (HPV) screening in the screening of women’s diseases. Methods A total of 1 718 women who performed general survey from January 2012 to January 2013 were selected as the research objects. The items included leucorrhea routine test, liquid-based cell test, gynecological B-mode ultrasound and breast ultrasonography. At the same time, Check, record and analyze the screening results. Count data using χ2 test, P <0.05 for the difference was statistically significant. RESULTS: Of the 718 censuses, 52.8% were diagnosed as normal, 14.2% were diagnosed as HPV (+), atypical squamous cell lesions were 7.2%, vaginitis was 4.3%, uterine fibroids were 7.1%, breast diseases were 13.3%, low Squamous intraepithelial lesion 1.2%. 244 cases of HPV (+), 30 to 39 years old accounted for 39.8%, 40 to 49 years old accounted for 34.8%, the incidence was higher than other age groups. In 244 cases of HPV (+), 16 cases of cervical intraepithelial neoplasia (CIN) were confirmed by colposcopic biopsy with HPV-positive cervical cytology-based cytology abnormalities. Among them, 16 cases were diagnosed by cervical conization For carcinoma in situ. Conclusion Because HPV positive is closely related to the occurrence of cervical cancer, early screening can help further examination and diagnosis, early treatment and prevention programs to improve the prognosis of HPV-positive.