为了观察苏子提取物(EPS)对高脂饮食导致肝损伤家兔的保护作用,试验通过高脂饮食建立家兔非酒精性脂肪肝病模型,分别测定正常对照组(NC)、高脂模型组(HLM)、苏子提取物低剂量组(EPSⅠ,0.1 g/mL)和高剂量组(EPSⅡ,0.5 g/mL)家兔血清中丙氨酸氨基转移酶(ALT)和门冬氨酸氨基转移酶(AST)含量及评估肝组织脂肪变性程度。结果表明:EPS能极显著或显著降低血清中AST、ALT含量(P<0.01或P<0.05);显著减轻肝组织脂肪变性(P<0.05)。说明EPS具有抑制高脂饮食导致的肝脏损伤作用。 In order to observe the protective effect of EPS on liver injury caused by high-fat diet in rabbits, a non-alcoholic fatty liver disease model was established by high-fat diet. The normal control group (NC), high-fat model group Serum levels of alanine aminotransferase (ALT) and aspartate amino groups in HLM, SuSE extract low dose group (EPSⅠ, 0.1 g / mL) and high dose group (EPSⅡ, 0.5 g / Transaminase (AST) content and assess the degree of hepatic steatosis. The results showed that EPS could significantly reduce AST and ALT levels in serum (P <0.01 or P <0.05), and significantly reduce hepatic steatosis (P <0.05). Explain that EPS has the effect of inhibiting liver damage caused by high-fat diet.