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目的:研究分析盐酸川芎嗪辅助治疗慢性阻塞性肺气肿的临床效果。方法:择取2013.05-2014.05期间在我院接受治疗的50例慢性阻塞性肺气肿患者,利用抽签法将其分成2组,一组25例患者应用内科常规措施进行治疗设为对照组,一组25例患者在内科常规措施治疗的同时应用盐酸川芎嗪辅助治疗设为治疗组。结果:治疗组25例患者的总疗效率为92.0%(23/25)明显高于对照组的76.0%(19/25),差异P<0.05有统计学意义。治疗组患者的红细胞变形指数、血浆黏度、低切黏度以及高切黏度显著性小于对照组,差异P<0.05有统计学意义。结论:盐酸川芎嗪对慢性阻塞性肺气肿进行辅助治疗具有更为理想的效果,可有效降低血液粘滞程度,适用于临床治疗及推广。
Objective: To study the clinical effect of ligustrazine hydrochloride in the treatment of chronic obstructive pulmonary emphysema. Methods: Fifty patients with chronic obstructive pulmonary emphysema who were treated in our hospital from 2013.05 to 2014.05 were selected and divided into two groups according to the method of lottery. A group of 25 patients were treated with routine medical treatment as the control group Group of 25 patients in the medical treatment of conventional measures at the same time with ligustrazine hydrochloride adjuvant therapy as the treatment group. Results: The total effective rate of the 25 patients in the treatment group was 92.0% (23/25), which was significantly higher than that in the control group (76.0%, 19/25). The difference was statistically significant at P <0.05. Erythrocyte deformity index, plasma viscosity, low-shear viscosity and high-shear viscosity were significantly lower in the treatment group than in the control group, the difference P <0.05 was statistically significant. CONCLUSION: Tetramethylpyrazine hydrochloride is an effective adjuvant therapy for chronic obstructive pulmonary emphysema, which can effectively reduce the degree of blood viscosity and is suitable for clinical treatment and promotion.