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对喉癌、喉部良性疾病和正常人的血清铁蛋白(SF)和糖链蛋白(CA-50)进行了测定,发现喉癌SF水平明显升高(P<0.01)。经手术治疗后SF水平下降;但疗效差、肿瘤复发者SF水平则升高。SF还和喉癌的TNM分期有关,同血清铁无关。上述各组的CA-50水平均低于正常值17U/ml,组间比较亦无统计学差异(P>0.05)。提示SF和CA-50水平测定有一定的临床意义。
Serum ferritin (SF) and sugar chain protein (CA-50) levels in laryngeal cancer, benign diseases of the larynx, and normal persons were measured and it was found that SF levels in laryngeal cancer were significantly higher (P<0.01). After surgery, the level of SF decreased; however, the level of SF in patients with poor efficacy and tumor recurrence increased. SF is also associated with the TNM staging of laryngeal cancer and has nothing to do with serum iron. The CA-50 levels in the above groups were lower than the normal values of 17 U/ml, and there was no statistical difference between the groups (P>0.05). It is suggested that the SF and CA-50 levels have a certain clinical significance.