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本文以自由饮水给药方式进行了锶.硼和氟联合作用的亚急性实验，以探讨锶、硼对氟的拮抗作用。实验结果．给予小鼠200×10(-6)F-六个月后，可使其骨氟含量显著升高（PM＜0.01），肾碱性磷酸酶活力（ALP）显著增高（P＜0．01），4．5个月后血清碱性磷酸酶（ALP）活力亦显著增高（P＜0．01），同时给予80×10(-6)B(3+),100×10(-6)Sr(2+)时，可以显著降低骨氟含量，抑制血清、肾碱性磷酸酶的活力，表明锶与硼对氟存在拮抗作用。
In this paper, a free radical scavenging method was used to study the sub-acute effects of strontium, boron and fluorine in order to explore the antagonistic effects of strontium and boron on fluoride. Experimental results. After being given 200 × 10 (-6) F for 6 months, the content of bone fluoride increased significantly (P <0.01) and the activity of renal alkaline phosphatase (ALP) increased significantly (P <0.01) (P <0.01). At the same time, the activity of alkaline phosphatase (ALP) in serum of 80 × 10 (-6) B (3 +) and 100 × 10 (2+), it can significantly reduce the bone fluoride content, inhibit serum and renal alkaline phosphatase activity, indicating that strontium and boron on the fluorine antagonism.