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目的探讨手术+综合治疗治疗乳腺癌的临床疗效。方法回顾分析乳腺癌86例行手术+新辅助化疗、术后综合治疗的临床资料。结果行保乳术38例及改良根治术48例的患者均施行新辅助化疗,术后化疗、放疗,内分泌治疗等。术后随访83例,其3,5,8年生存率:保乳术组分别为97.3%,94.4%,38.2%;改良根治术组为95.7%,93.1%,36.6%,差异无统计学意义。复发率:保乳术组3,5,8年分别为0,5.6%,23.5%。改良根治术组为2.8%,6.8%,26.8%,差异无统计学意义。结论保乳术或改良根治术+新辅助化疗、术后化疗、放疗、内分泌治疗是提高乳腺癌生存率、减少复发率、改善生活质量的重要措施。
Objective To investigate the clinical efficacy of surgery + comprehensive treatment of breast cancer. Methods Retrospective analysis of 86 cases of breast cancer surgery + neoadjuvant chemotherapy, postoperative comprehensive treatment of clinical data. Results 38 cases of conservative surgery and modified radical mastectomy in 48 patients were performed neoadjuvant chemotherapy, postoperative chemotherapy, radiotherapy, endocrine therapy. 83 cases were followed up for 3, 5 and 8 years. Survival rates at 3, 5 and 8 years were 97.3%, 94.4% and 38.2% respectively in the conservative treatment group and 95.7%, 93.1% and 36.6% in the modified radical operation group, with no significant difference . Recurrence rate: 3, 5, 8 years after breast-conserving surgery were 0, 5.6% and 23.5% respectively. Modified radical mastectomy group was 2.8%, 6.8%, 26.8%, the difference was not statistically significant. Conclusions It is an important measure to improve breast cancer survival rate, reduce recurrence rate and improve quality of life in breast conserving surgery or modified radical mastectomy + neoadjuvant chemotherapy, postoperative chemotherapy, radiotherapy and endocrine therapy.