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用透射电镜研究了伯氏疟原虫入侵红细胞的过程,并与约氏疟原虫进行了比较。结果表明,入侵开始时,裂殖子多以顶端对着红细胞,并显示出调整方向的能力;红细胞也有部分突出等主动性反应。裂殖子接触后,红细胞即形成凹陷,逐渐将其包围。在此过程中,裂殖子通过顶端和表被两种不同的附着方式与凹陷壁保持联系。包围完成后,凹陷口融合封闭,变成一个包着入侵裂殖子的游离囊泡。与此同时,某些细胞成分也发生一定的变化。 约氏疟原虫多感染幼龄红细胞,且虫体被凹陷口勒出缢痕。伯氏疟原虫则多入侵成熟红细胞,无缢痕现象。
Transmission electron microscopy was used to study the invasion of P. berghei into erythrocytes and compared with Plasmodium yoelii. The results showed that at the beginning of invasion, merozoites were mostly confronted with erythrocytes and showed the ability to adjust their orientation; red blood cells also showed some prominent proactive responses. After the contact of merozoites, erythrocytes formed a depression that gradually surrounded it. During this process, the merozoites remain in contact with the dimple wall through the two different attachments of the tip and the table. After the encirclement is complete, the degenerated mouth merges and becomes a free vesicle with invading merozoites. At the same time, certain cellular components also undergo some changes. Polycyclica-polygamia infection of juvenile red blood cells, and parasites were hollow mouth marks out. P. berghei is more invasion of mature red blood cells, no signs of scarring.