1 背景 抗疟药用于治疗类风湿关节炎(RA)已有几十年的历史了,虽然过去学者们报道了一些临床试验结果,但通常试验样本量较小,试验结果有较大的偏性,而且有些试验中所采用的剂量较现在所接受的剂量要大。近10年来,陆续发表了一些较大样本,设计较合理的临床试验研究,这些新的试验评价了羟 BACKGROUND Antimalarial drugs have been used for the treatment of rheumatoid arthritis (RA) for decades. Although some scholars have reported some clinical trials in the past, the test sample size is usually small and the test results have a larger bias Sexually, and in some trials the dose used is greater than the current accepted dose. The past 10 years, one after another published some larger samples, the design of a more rational clinical trial studies, these new test evaluation of the hydroxyl