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在子宫平滑肌瘤与肉瘤之间存在一组交界性肿瘤,包括子宫富于细胞型、奇异型、核分裂活跃型、不典型及恶性潜能未定型平滑肌瘤。本研究对原诊断为子宫富于细胞型平滑肌瘤42例,进行重新诊断,同时收集其临床资料并随访。结果:42例中,富于细胞型平滑肌瘤5例,奇异型平滑肌瘤1例,不典型平滑肌瘤7例,恶性潜能未定型平滑肌瘤2例,肉瘤1例及普通平滑肌瘤26例。在细胞丰富的基础上,细胞异型与核分裂的关系密切;不同月经周期的细胞异型及核分裂变化不显著;交界性平滑肌瘤的临床特征与普通平滑肌瘤相同,预后良好。病理诊断子宫交界性平滑肌瘤应综合细胞丰富、细胞异型及核分裂三项组织学特征,其临床处理可同普通平滑肌瘤,但有必要作进一步研究。
There is a group of borderline tumors between uterine leiomyomas and sarcomas, including uterine cell rich, singular, mitotic active, atypical and malignant potential undetermined leiomyomas. In this study, the original diagnosis of uterine rich cell leiomyoma in 42 cases, to re-diagnose, while collecting the clinical data and follow-up. Results: Among the 42 cases, 5 were rich in leukama leiomyoma, 1 was singular leiomyoma, 7 were atypical leiomyoma, 2 were malignant latent leiomyoma, 1 was sarcoma and 1 was common leiomyoma 26 cases. On the basis of cellular abundance, the relationship between cell atypia and mitosis is close; the abnormal cell shape and mitotic division in different menstrual cycles are insignificant; the clinical features of borderline leiomyoma are the same as that of ordinary leiomyoma, and the prognosis is good. Pathological diagnosis of borderline uterine leiomyoma should be integrated cell abundance, cell dystrophy and mitotic three histological features, the clinical treatment with ordinary leiomyoma, but it is necessary for further study.