髓母细胞瘤是颅内恶性胶质瘤的一种,其儿童发病率约占小儿所有脑肿瘤的20％左右。此肿瘤细胞活跃,呈浸润性生长,且有沿脑脊液广泛播散、种植的特点。传统的治疗观点是外科手术加全脑和脊髓放疗,但该肿瘤多生长于小脑蚓部或位于小脑半球,部分病例侵及脑干,开颅手术难以切净病灶。即使术后放疗多数病人仍可复发,再手术更加困难,预后效果不好。 Medulloblastoma is a kind of intracranial malignant glioma, the incidence of children accounts for about 20% of all brain tumors in children. The tumor cells are active, invasive growth, and along the cerebrospinal fluid widely disseminated, planting characteristics. Traditional treatment point of view is surgery plus whole brain and spinal cord radiotherapy, but the tumor grew in the cerebellar vermis or in the cerebellar hemispheres, some cases of invading the brainstem, craniotomy difficult to cut net lesions. Even after the majority of patients with postoperative radiotherapy can still relapse, reoperation more difficult, the prognosis is not good.