治疗新生儿呼吸衰竭的重要手段是机械通气,但随着呼吸机的广泛应用,呼吸机相关性肺炎(venti-lation-associated pneumonia VAP)也随之增多。VAP是指经气管插管机械通气48 h后出现的医院获得性肺炎,是机械通气常见的并发症,可造成撤机困难,延长住院时间,增加医疗费用,甚至导致机械通气失 An important means of treating neonatal respiratory failure is mechanical ventilation. However, with the widespread use of ventilators, ventilator-associated pneumonia (VAP) also increases. VAP is a hospital-acquired pneumonia that occurs 48 hours after mechanical ventilation through the endotracheal tube and is a common complication of mechanical ventilation, which can result in difficulties in weaning, extended hospitalization, increased medical costs, and even mechanical ventilation