目的重点研究WI的方法学问题,期望对WI的临床推广应用有所帮助。方法查阅文献,结合临床的应用体会,从ET与WI技术的关系、多普勒取样门大小、多普勒流速曲线的奈奎斯特现象、时间分辨力、呼吸、血压、心律不齐、心率等9个因素对WI的影响进行方法学研究。结果上述9种因素对WI均有影响。结论WI有两个主要变量,即动脉管壁的波动和管腔内血流流动,在为临床提供大量有用诊断信息的同时,也出现了一些干扰因素,后者可以通过方法学研究加以控制。 Purpose To study the methodological issues of WI and expect to be helpful for clinical application of WI. Methods According to the literatures and clinical experiences, the relationship between ET and WI, the size of Doppler sampling gate, the Nyquist phenomenon of Doppler velocity curve, time resolution, respiration, blood pressure, arrhythmia, heart rate And other 9 factors on the impact of WI methodological research. Results The above-mentioned 9 factors have an impact on WI. Conclusion There are two main variables of WI, that is, the fluctuation of arterial wall and the flow of blood in lumen. While providing lots of useful diagnostic information for clinic, some disturbing factors also appear. The latter can be controlled by methodological study.