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我地区与广西接壤,居住着汉、回、苗、瑶等多种民族,向有近亲婚配的习惯。1980年调查2268人,发现β-地中海贫血、血红蛋白病、红细胞G-6-PD缺陷、球形红细胞增多症及糖酵解酶类缺乏所致的贫血,在邵阳区并非罕见,调查部份家系证明近亲婚配是遗传性贫血发病的重要因素。 一、地中海贫血 调查2268人中,发现重型β地中海贫血3例,轻型及静止型25例(占1.2%)。在转诊患者中又发现重型β—地中海贫血9例、中间型5例、轻型9例,两项共计51例。未发现α—地中海贫血。
My area borders Guangxi and lives in many ethnic groups such as Han, Hui, Miao and Yao, and has the habit of marrying relatives. Survey of 2268 people in 1980, found that β-thalassemia, hemoglobin disease, erythrocyte G-6-PD defects, polycythemia and glycolysis caused by lack of anemia, is not uncommon in Shaoyang, the investigation of some families that Inbreeding is an important factor in the development of hereditary anemia. First, the Mediterranean anemia survey 2268 people, found that 3 cases of β-thalassemia major, 25 cases of light and static type (1.2%). In the referral patients, 9 cases of β-thalassemia major were found, 5 cases were intermediate, 9 cases were light and 51 cases were two. Alpha-thalassemia was not found.