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笔者近年来应用异搏定与本妥英纳合用治疗顽固性房性早搏,收到良好的效果,现报道如下。1 临床资料1.1 病例选择 本组80例,男47例,女33例,年龄16～68岁。病因为心肌炎(30例),冠心病(24例)、心肌病(5例)、肺心病(5例)。病人在单用异搏定或苯妥英钠无效后,二药联合使用。试验前停用各种抗心律失常药>5个半衰期。入选者经Holter(动态心电图)监测房性早搏总数>3000个/24h。在病因治疗基础上应用异搏定40 mg、苯妥英钠0.1口服一日三次连用5天。治疗前后观察心电图变化,检测心、肝、肾功能。治疗结束时复查Hoter。
In recent years, the author application of verapamil and the Benoyingna combined treatment of refractory atrial premature beats, received good results, are reported below. 1 Clinical data 1.1 Case Selection This group of 80 patients, 47 males and 33 females, aged 16 to 68 years. The cause of myocarditis (30 cases), coronary heart disease (24 cases), cardiomyopathy (5 cases), pulmonary heart disease (5 cases). After the patient is treated with verapamil or phenytoin alone, the two drugs are used in combination. Discontinue various antiarrhythmic drugs> 5 half-lives before trial. Participants monitored atrial premature beats totaling> 3000 cells / 24h by Holter. In the treatment based on the application of verapamil 40 mg, 0.1 sodium phenytoin three times a day for 5 days. ECG changes before and after treatment to detect heart, liver and kidney function. Review the Hoter at the end of treatment.