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目的对比观察不稳定性心绞痛和非ST段抬高心肌梗死患者早期应用经皮冠状动脉介入治疗和药物治疗的疗效,选择最佳治疗方案。方法选择我院心内科住院的患者共272例,分为早期药物保守治疗组和早期介入治疗组。随访患者1~24个月的心绞痛复发率、再次入院率和再次介入治疗率或血管搭桥术,以及心源性死亡和(或)急性心肌梗死发生率。结果介入治疗组心源性死亡和(或)急性心肌梗死发生率较药物治疗组显著降低,介入治疗组在心绞痛复发率、再住院率方面同药物保守组比较均显著降低(P<0.001)。结论早期经皮冠状动脉介入治疗能显著改善不稳定性心绞痛和非ST段抬高心肌梗死患者的预后。
Objective To compare the efficacy of early percutaneous coronary intervention and drug therapy in patients with unstable angina and non-ST-segment elevation myocardial infarction and choose the best treatment. Methods A total of 272 patients hospitalized in our hospital were divided into two groups: conservative treatment group and early intervention group. Patients were followed up for 1 to 24 months of angina recurrence rate, re-admission and re-intervention rate of treatment or bypass, and cardiac death and (or) the incidence of acute myocardial infarction. Results The incidence of cardiac death and / or acute myocardial infarction in the intervention group was significantly lower than that in the drug-treated group. The intervention group had significantly lower recurrence rate and hospitalization rate compared with the conservative group (P <0.001). Conclusion Early percutaneous coronary intervention can significantly improve the prognosis of patients with unstable angina and non-ST-elevation myocardial infarction.