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目的探讨结肠癌伴肝转移行同期切除影响病人预后的相关因素。方法回顾性分析2002年1月至2008年6月第二军医大学附属东方肝胆外科医院综合治疗三科结肠癌伴肝转移行同期切除59例的临床资料。结果年龄、性别、CEA水平、门静脉化疗泵内局部化疗及肝转移灶大小、数目和位置对病人生存时间具有影响。结论肝肿瘤的大小、位置、数目、CEA水平虽对预后有影响,但均为不可控因素,而术中及术后门静脉化疗泵内局部化疗为可控因素。术中及术后门静脉化疗泵内局部化疗并配合全身化疗者预后明显好于未给予者(P=0.0076)。
Objective To investigate the related factors that affect the prognosis of patients with colon cancer accompanied with liver metastasis and resection at the same time. Methods The clinical data of 59 patients with three colon cancer with liver metastasis and resection of liver in the Eastern Hepatobiliary Surgery Hospital affiliated to the Second Military Medical University from January 2002 to June 2008 were retrospectively analyzed. Results Age, gender, CEA level, local chemotherapy and hepatic metastases size, number and location within the portal vein chemotherapy pump had an impact on the patient’s survival time. Conclusions Although the size, location, number and CEA level of liver tumor have an impact on the prognosis, they are uncontrollable factors. Local chemotherapy in intraoperative and postoperative portal vein chemotherapy pumps is a controllable factor. Intraoperative and postoperative portal vein chemotherapy pump local chemotherapy combined with systemic chemotherapy prognosis was significantly better than the non-given (P = 0.0076).