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对安梦（褪黑素）胶囊进行安全性毒理学评价。方法：用每克饲料中含８．３３、１６．６７、３３．３３ｍｇ安梦（褪黑素）胶囊内容物的低、中、高剂量组 ３０ ｄ喂养大鼠。结果：当剂量小于或等于每克饲料含 １６． ６７ ｍｇ安梦（褪黑素）胶囊内容物时，试验组的各项指标未发现异常，当剂量为３３．３３ ｍｇ时所有动物活动明显减少，常处于睡眠状态，摄食明显少于其它各组；体重和血红蛋白、红细胞压积均低于正常对照组。无作用剂量组为中剂量组。最大无作用剂量为 ２． ７６ ｇ／（ｍｍ· ｄ）。结论：一定剂量的安梦（褪黑素）胶囊安全可靠，对人体无副作用。
A safety (melatonin) capsules for safety and toxicological evaluation. METHODS: Rats were dosed for 30 days with low, medium, and high doses of 8.33, 16.67, 33.33 mg of anamorphic (melatonin) capsule per gram of feed. Results: When the dose is less than or equal to 16 per g feed. 67 mg An Meng (melatonin) capsule content, the test group showed no abnormalities in all indicators, when the dose of 33.33 mg significantly reduced the activity of all animals, often in sleep, eating significantly less than the other groups ; Body weight and hemoglobin, hematocrit were lower than the normal control group. No role in the dose group for the dose group. The maximum no dose of 2. 76 g / (mm · d). Conclusion: A certain dose of An Meng (melatonin) capsules safe and reliable, no side effects on the human body.