Objective: To evaluate the therapeutic effect of Nd:YAG laser under urethroscope for the treatment of intraurethral Candyloma Acuminata (CA) in males.Method: Nd:YAG laser under urethroscope was employed to remove the warts.Result: Seventeen patients out of eighteen cases with CA were cured after the first procedure. The ure rate was 94.4%.For second treatment, the cure rate was 100% and no relapse occurred after observation for 12 - 4 months.Conclusion: Nd:YAG laser by urethroscope is a very good method for the treatment of intraurethral CA.