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1033例痰涂片5次阴性、X线判定活动的初怡肺结核成年中国病人(其中370例培养阳性)随机分为1.SC组(选择化疗组),该组病人直至痰培养阳性或X线、临床恶化才开始给用SPH/S_2H_2方案治疗(见第4组);2.2SHRZ组,每日用链(S)、肼(H)、利(R)、吡(Z)二个月;3.3SHRZ组,使用药物同2,但疗期为3个月;4.SPH/S_2H_2组,头3个月每日链、肼、柳(P)、随后9个月周二次的S和H,本组为对照方案。截至30个月,选例时痰培养阴性病人中,SC组病人有53％(细菌学证实者40％)证明病变确系活动而
1033 cases of sputum smear 5 negative, X-ray determination of active cough tuberculosis in early adult Chinese patients (of which 370 cases of culture positive) were randomly divided into 1.SC group (chemotherapy group) until the sputum culture positive or X-ray , Clinical deterioration began to be treated with SPH / S_2H_2 regimen (see group 4); 2.2SHRZ group, daily use of chain (S), hydrazine (H), Lee SHRZ group, the same medication with 2, but the treatment period was 3 months; 4. SPH / S_2H_2 group, the first three months daily chain, hydrazine, Liu (P), followed by 9 months and two weeks of S and H, Group as a control program. As of 30 months, 53% of patients in the SC group (40% of bacteriologically confirmed) of sputum culture negative patients at the time of selection demonstrated that the disease was indeed active