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作者对59例脑转移瘤的治疗效果作了研究,计来自肺癌42例(71.2%),乳癌4例(6.8%),胃癌、结肠癌各3例(5.7%)。肺癌的组织分型:腺癌16例(38%),小细胞癌12例(28.6%),鳞状上皮癌8例(19%)。男39例,女20例。年龄1个月～78岁。使用线性加速器10MeV X线左右对穿双侧全脑照射50Gy(2Gy/日,5日/周),剂量在40Gy以下时,局部再照射20Gy。结果见到,神经症状及神经功能改善率分别为78%,50%。CT图象上肿瘤完全消失者(CR)16例(32%),缩小50%以上者(PR)16例(32%),CR与PR有效率为64%。缩小不足50%者(NC)17例(34%),进展者(PD)1例(2.0%)。50%病例生存期限为5个月,16%病例生存1年。原发灶乳癌比肺癌
The authors studied the therapeutic effects of 59 cases of brain metastases, including 42 cases (71.2%) of lung cancer, 4 cases (6.8%) of breast cancer, and 3 cases (5.7%) of gastric cancer and colon cancer. The classification of lung cancer was adenocarcinoma in 16 cases (38%), small cell carcinoma in 12 cases (28.6%), and squamous cell carcinoma in 8 cases (19%). 39 males and 20 females. Age 1 month to 78 years old. Using a 10 MeV X-ray linear accelerator, the entire brain was irradiated with 50 Gy (2 Gy/day, 5 days/week) on both sides, and when the dose was below 40 Gy, 20 Gy was locally irradiated. The results showed that the neurological symptoms and neurological function improvement rates were 78% and 50%, respectively. There were 16 patients (32%) with complete tumor disappearance (CT) on the CT image, 16 (32%) with more than 50% reduction (PR), and 64% with CR and PR. Less than 50% of the cases were narrowed (NC) in 17 cases (34%), and progressors (PD) in 1 case (2.0%). In 50% of cases, the survival period is 5 months, and 16% of cases survive for 1 year. Primary breast cancer than lung cancer