微粉学(Micromeritics)是新发展的一门独立的科学,其研究对象主要是关于微细的固体粒子及其集合体所表现出的各种理化性质等。过去认为,象“粉碎”那样利用外力手段去克服物体分子的内聚力而使“大物”变“小物”的所谓物理变化,没有什么研究和实用价值。其实不然,近年来有人研究发现:当固体变成微粉(即固体微细粒子的集合体)后,由于单位容积或重量物质的表面积急剧增大而出现一些“意想不到”的特征。其中有:力学现象,如微粉的堆积、流动与充填、空隙率等;物理现象,如微粉的导电、导热、摩擦带电等;化学现象,如微粉与气体、液体以及微粉之间的反应、微粉的吸附现象等。在药剂工作中,经常遇到药物的微粒,如散剂、胶囊剂、片剂、粉末安瓿等。微粉 Micromeritics is a newly developed independent science. Its research object mainly focuses on various physical and chemical properties of fine solid particles and their aggregates. In the past, the so-called physical changes that made the “big thing” into a “little thing” by using external means to overcome the cohesion of objects like the “smashing” did not have any research or practical value. In actual fact, in recent years, some studies have found that when the solid becomes a fine powder (ie, a collection of solid fine particles), some “unexpected” features occur due to the sharp increase of the surface area per unit volume or weight of the material. There are: mechanical phenomena, such as the accumulation of fine powder, flow and filling, porosity, etc .; physical phenomena, such as the conductivity of fine powder, thermal conductivity, frictional electrification; chemical phenomena such as the reaction between fine powder and gas, liquid and fine powder, The phenomenon of adsorption and so on. In pharmaceutical work, often encounter the drug particles, such as powders, capsules, tablets, powder ampoules and so on. Powder