论文部分内容阅读
利用透射电子显微镜观察了氯化镓对人胃癌细胞株 MGc80 - 3细胞凋亡的诱导作用。结果发现 :GC可诱导 MGc80 - 3细胞凋亡 ,且有浓度依赖性。低、中浓度 GC可引起癌细胞凋亡早期电镜形态改变。高浓度 GC可引起凋亡晚期形态改变 ,而且还可引起细胞坏死。结果提示 :GC诱导 MGc80 - 3细胞凋亡发生是其抑制瘤细胞生长的机制之一。
Transmission electron microscopy was used to observe the effect of lanthanum chloride on the apoptosis of human gastric cancer cell line MGc80-3. The results showed that: GC can induce apoptosis of MGc80-3 cells in a concentration-dependent manner. Low and medium concentrations of GC can cause apoptosis of cancer cells in the early stage of electron microscopy. High concentrations of GC can cause late morphological changes in apoptosis, but also can cause cell necrosis. The results suggest that GC-induced apoptosis of MGc80-3 cells is one of the mechanisms that inhibit the growth of tumor cells.