论文部分内容阅读
地方性克汀病(以下简称克汀病)被公认的主要病因是环境缺碘。但因某些现象未能解释,故有“遗传-缺碘”病因假说,疑为多基因遗传病。为了探讨此假说的可能性,1979年至1982年我们在贵州地方甲状腺肿(以下简称地甲肿)和克汀病流行区进行了群体遗传学调查,现将结果报告于后。对象及方法在贵州省麻江县河坝公让,都匀县石龙公社,紫云县猴场公社及望谟县纳夜公社并城郊东岩大队(以下简称望谟)四个地方,进行地甲肿和克汀病普查时,随机对部份克汀病人和
Local cretinism (hereinafter referred to cretinism) is recognized as the main cause of iodine deficiency in the environment. However, due to some phenomena can not explain, it is “genetic - iodine deficiency” cause hypothesis, suspected polygenic disease. To explore the possibility of this hypothesis, we conducted a population genetic survey of endemic goiter and cretinism in Guizhou from 1979 to 1982, and the results are reported hereafter. Subjects and methods were carried out in four places, Heba Gongzhun, Majiang County, Guizhou Province, Shilong Commune, Duyun County, Monkey Farm Commune, Ziyun County and Nanyun Commune in Wangmo County and Eastern Yancheng Suburb (hereinafter referred to as Wangmo) Gendicine and cretinism during the general survey of patients and part of cretinism