选择 1997年度全年住院死亡病例共 2 15例 ,逐例审查病程记录、死亡病例讨论及死因分析记录、按药物不良反应定义及判定标准 ,确定有无药物不良反应及其对死亡的影响 ,本文仅统计造成直接死因或严重影响病情 ,加速死亡的药物不良反应。1　临床资料1 1　发生率　全院 1997年住院 A total of 215 cases of hospitalized deaths in 1997 were selected. Case history, death case discussions, and death cause analysis records were reviewed on a case-by-case basis. According to the definition and criteria of adverse drug reactions, adverse drug reactions and their effects on death were determined. Only count adverse drug reactions that cause direct cause or severely affect the condition and accelerate death. 1 Clinical data 1 1 Incidence of hospitalization in 1997