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目的:探究全子宫切除术和筋膜内子宫切除术对术后患者内分泌功能的影响。方法:选取64例行子宫切除术患者为研究对象,根据患者的手术方式,将患者分为全子宫切除术组(A组)、筋膜内子宫切除术组(B组)。分别检测患者术前、术后6个月,术后12个月的血清促卵泡素(FSH)、黄体生成素(LH)、雌二醇(E2)、孕酮(P)、睾酮(T)评价患者术后的卵巢功能。结果:患者行子宫切除术后血清促卵泡素和黄体生成素都有升高,术后12个月比较术后6个月上升明显,且雌二醇和孕酮的表达下降,术后12个月下降更明显,与全子宫切除术比较,筋膜内子宫切除术后患者各项激素水平的变化小。结论:筋膜内子宫切除术可以更好地减轻对卵巢功能的影响,维持卵巢的内分泌功能。
Objective: To investigate the effect of total hysterectomy and intrafascial hysterectomy on the endocrine function of postoperative patients. Methods: Sixty-four patients undergoing hysterectomy were enrolled in this study. Patients were divided into total hysterectomy group (A group) and fascia hysterectomy group (B group) according to the operation mode of the patients. The levels of serum FSH, LH, E2, Progesterone (P) and testosterone (T) in patients before operation, 6 months after operation and 12 months after operation were measured respectively. Ovarian function after surgery. Results: The serum follicle stimulating hormone and luteinizing hormone in patients underwent hysterectomy both increased. The levels of serum estradiol and progesterone decreased significantly at 12 months after operation and decreased more at 12 months Obviously, compared with total hysterectomy, intrafascial hysterectomy in patients with small changes in the level of hormones. Conclusion: Fascia hysterectomy can better reduce the impact on ovarian function and maintain ovarian endocrine function.