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由于等待肝移植的患者越来越多，而可用于移植的肝脏严重短缺，故提高边缘供肝的质量对于增加供肝来源具有重要意义。提高边缘供肝质量的最新研究包括对供体的药物干预及循环支持、肝脏保存液的改进、机械灌注的尝试和更加合适的保存温度以及气态氧灌注的进一步改进。但其中大部分都局限在动物研究阶段，其与临床应用还存在一定的差距。该文就提高边缘供肝质量的研究新进展予以综述。“,”There is a contradiction between the increasing patients waiting for liver transplantation and the shortage of donor liver,it is important to increasing the number of donor livers by improving the quality of the marginal donor liver.The new researches of improving the quality of the marginal donor liver include:the medica-tion and the circulation support for the donor,the modified preserving solution,the use of machine perfusion pres-ervation,the research of the best temperature for liver graft storage and the improving of gaseous oxygen perfusion. However,most of the researches are still in animal experiment stage,where a certain gap still exist to clinical application.Here is to make a review of the recent progress in improving the quality of marginal donor liver .