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目的:探讨晚期早产儿的围产期相关高危因素及新生儿期并发症、死亡率的临床现况。方法:对2005~2010年收治的499例晚期早产新生儿的临床资料进行回顾性分析、研究。结果:胎膜早破、羊水异常、脐带异常、妊娠期高血压疾病及妊娠期糖尿病是晚期早产儿发生的主要高危因素,并发症以黄疸最为多见,其次为新生儿呼吸窘迫综合征及新生儿肺炎。死亡原因中以呼吸衰竭为首,导致呼吸衰竭的病因主要是肺出血及呼吸窘迫综合征。结论:切实加强高危孕妇的围产期监督,可以减少晚期早产儿的出产,完善晚期早产儿出生后的管理是提高晚期早产儿的生存质量、降低死亡率的关键。
Objective: To investigate the perinatal related risk factors and neonatal morbidity and mortality in advanced preterm infants. Methods: The clinical data of 499 neonates with preterm birth in the late period of 2005-2010 were analyzed retrospectively. Results: Premature rupture of membranes, abnormal amniotic fluid, abnormal umbilical cord, hypertensive disorder of pregnancy and gestational diabetes mellitus were the main risk factors of preterm infants in late stage. The most common complication was jaundice, followed by neonatal respiratory distress syndrome and neonatal Pneumonia. Respiratory failure led to the cause of death, leading to respiratory failure mainly due to pulmonary hemorrhage and respiratory distress syndrome. CONCLUSIONS: Effectively enhancing perinatal surveillance in high-risk pregnant women can reduce the production of late preterm infants and improve the management of postpartum preterm infants. It is the key point to improve the quality of life and reduce the mortality of premature infants.