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目的观察局部晚期食管癌患者行调强放疗的疗效。方法选取2009年1月-2012年8月我院行调强放疗的食管癌患者46例,GTV包括原发病灶+转移淋巴结,CTV包括GTV+淋巴结引流区,PTV在CTV基础上各外放0.5cm。95%等剂量曲线包靶区,两肺V20≤25-30%,心脏平均剂量≤30GY,脊髓最大剂量<45GY。治疗计划采用5-9个照射野,常规分割1.8-2.0GY/次,DT60-64GY,随访时间截止于2013年8月1日。结果放疗后1-3个月观察食管癌消退情况,其中CR43.49%,PR50%,SD6.52%;患者1、2、3年生存率分别为85.3%、72.5%、54.6%;放疗不良反应主要以1-2级为主。结论调强放疗治疗食管癌近期疗效好,毒副反应可耐受。
Objective To observe the effect of intensity modulated radiotherapy in patients with locally advanced esophageal cancer. Methods Forty-six patients with esophageal cancer who underwent intensity modulated radiotherapy from January 2009 to August 2012 were selected. GTV included primary lesion and metastatic lymph nodes, CTV included GTV + lymph node drainage area, PTV was 0.5cm . 95% isodose curve package target area, both lung V20 ≤ 25-30%, the average heart dose ≤ 30GY, spinal cord maximum dose <45GY. Treatment plans using 5-9 irradiation field, conventional segmentation 1.8-2.0GY / times, DT60-64GY, follow-up time ended on August 1, 2013. Results The regression of esophageal cancer was observed 1-3 months after radiotherapy, with CR43.49%, PR50% and SD6.52%. The 1, 2 and 3-year survival rates were 85.3%, 72.5% and 54.6% respectively. Radiotherapy was poor The main reaction to 1-2 level. Conclusion Intensive radiotherapy for esophageal cancer has a good curative effect in the near future, and the toxic side effects can be tolerated.