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成人型多囊肾病（ＡＰＫＤ）是一种常染色体显性遗传病，其基因突变定位在第１６染色体短臂１区３带的ＰＫＤ１位点［１］，后来发现ＡＰＫＤ存在遗传异质性，定位了ＰＫＤ２、ＰＫＤ３位点［２、３］。国际上常用的ＰＫＤ１位点相邻的微小卫星体 ＤＮＡ ＳＭ７为遗传标记本研
Adult polycystic kidney disease (APKD) is an autosomal dominant genetic disease whose genetic mutation is located at the PKD1 locus 1 in zone 3 of the short arm of chromosome 16 [1]. Later, it was found that APKD has genetic heterogeneity and localization PKD2, PKD3 sites [2,3]. Internationally used PKD1 locus adjacent to the microsatellite DNA SM7 genetic markers of this research