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扁平苔藓(LP)组织学特征是伴有真皮淋巴细胞(主要是Ia阳性细胞)浸润的表皮改变。为了弄清LP的原发过程是基底角朊细胞的损伤还是目前尚未明确的抗原活化T淋巴细胞,而引起角朊细胞破坏的一种迟发超敏反应,作者从临床和组织学上已确诊为LP的6例男性患者,每人于受累区及未受累区取2mm钻孔的皮肤5份,2份移于鼠龄2～3个月的Balb裸鼠身上,3份作免疫荧光、组织学检查及多巴染色。于移植后的14天和21天取
The histological features of lichen planus (LP) are epidermal changes accompanied by infiltration of dermal lymphocytes (mainly Ia-positive cells). In order to understand whether the primary process of LP is basal keratinocyte injury or is currently uncleared by antigen-activated T lymphocytes, a late-onset hypersensitivity reaction that causes keratinocyte destruction, the author has been clinically and histologically confirmed For 6 male patients who were LP, 5 of them were taken from the affected area and the non-involved area with 2mm drilled skin, 2 were transferred to Balb nude mice aged 2 to 3 months, and 3 were used for immunofluorescence and tissue. Check and dopa staining. 14 days and 21 days after transplantation