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近年来,血管扩张药物治疗某些心力衰竭取得了较好的效果,其作用主要有 i 扩张小静脉使左心室充盈压明显下降。ii 扩张小动脉使左心室面对的喷射阻抗减小。iii 由于心脏的前后负荷减轻,心肌的氧耗和代谢得到改善。临床上首先在心肌梗塞使用。可以缩小心肌梗塞的范围。现在还用于慢性顽固性心力衰竭、二尖瓣或主动脉瓣关闭不全所致返流、室间隔缺损所致左～右分流以及高度二尖瓣狭窄所致的肺郁血等。
In recent years, vasodilator drugs to treat some of the heart failure has achieved good results, its main role i dilated venules to make a significant decrease in left ventricular filling pressure. ii Dilation of the arterioles reduces the ejection impedance confronting the left ventricle. iii Myocardial oxygen consumption and metabolism are improved due to reduced anterior and posterior cardiac load. The first clinical use of myocardial infarction. Can narrow the scope of myocardial infarction. Now also used for chronic intractable heart failure, mitral regurgitation caused by inadequate mitral or aortic regurgitation, left ventricular septal defect due to left shunt and a high degree of mitral stenosis caused by lung depression and so on.