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报道了2例成功地应用肉毒毒素A(BTA)治疗腋部多汗症的病例,并首次定量地测定治疗前后汗液的分泌量。 2例病人均在10余岁时开始出现腋部多汗,病程分别为22和27年,在就诊前从未接受过药物治疗,其中1例病人的促甲状腺激素略高。他们分别接受了两侧腋部各50U的BTA皮下注射,每个腋下分2～3个注射点,注射5d内多汗均得以控制,通过称量滤纸吸收汗液前后的重量改变确定汗液量,分别测定治疗前、后2～4周的分泌量,发现静息时
Two cases of successful treatment of axillary hyperhidrosis with botulinum toxin A (BTA) were reported, and the amount of sweat secretion was measured quantitatively for the first time. Both of the 2 patients started to have axillary hyperhidrosis when they were over 10 years of age, with durations of 22 and 27 years respectively. They had never received any medical treatment before their visit. One patient had slightly elevated thyrotropin. They received subcutaneous injection of 50U of BTA on each side of the axilla, respectively, 2 to 3 injection points in each armpit. Sweat was controlled within 5 days after injection. The amount of sweat was determined by weighing the change of weight before and after sweat absorption, Were measured before and after 2 to 4 weeks of secretion, found at rest