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用大肠杆菌复制ASC家兔模型,测定其血清LDH及其同功酶,并取肝、肺、肾、心等作病理检查.结果表明,ASC组(8只)中的LDH明显高于对照组(7只P<0.005);前者死亡6只的LDH显著大于存活的2只(P<0.01),其中ASC组的LDH_4和LDH_5均高于对照组,以LDH_4为明显(P<0.005),与病理结果中肝病变明显、肺肾轻微、心无改变相近似.上述提示,ASC时组织器官损伤明显,以肝为早且重,LDH及其同功酶对估计ASC的预后和重要器官损伤的程度及顺序有一定帮助。
Escherichia coli was used to replicate ASC rabbit model, serum LDH and its isoenzymes were measured, and liver, lung, kidney, heart, etc. were taken for pathological examination. The results showed that LDH in ASC group (8) was significantly higher than the control group. (7 P<0.005); LDH of 6 of the former died significantly greater than 2 of the surviving (P<0.01), in which LDH_4 and LDH_5 of ASC group were higher than those of the control group, and LDH_4 was significant (P<0.005). The pathological results showed obvious liver lesions, slight lung and kidney, no change in heart similar. The above tips, ASC tissue damage is obvious, the liver is early and heavy, LDH and its isozymes to estimate the prognosis of ASC and important organ damage The degree and order have some help.