有机锗化合物Ge-201水溶液小鼠经口LD_(50)为10512mg/kg,大鼠经口LD_(50)大于7g/kg。长期毒性试验大鼠随饲料进食本品1110,380,108,37m8/kg90天。110mg/kg组体重明显下降,脏器系数增大,90％的动物死亡,肾和肝发生器质性病变伴血清尿素氮增高。380mg/kg组部份动物出现轻度的肾小管上皮变性。108,37mg/kg组无异常。 The oral LD_(50) of the organogermanium compound Ge-201 aqueous solution was 10512 mg/kg, and the oral LD_(50) was greater than 7 g/kg. Long-term toxicity test Rats consumed 1110,380,108,37m8/kg for 90 days with feed. In 110 mg/kg group, the body weight decreased significantly, the organ coefficient increased, and 90% of the animals died. The renal and hepatic nephrogenic lesions were associated with increased serum urea nitrogen. Some of the animals in the 380 mg/kg group showed mild tubular epithelial degeneration. There were no abnormalities in the 108 and 37 mg/kg groups.