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给一患者用尿素治疗失代偿性肝硬化顽固性腹水低钠血症疗效满意。该患者系男性54岁,原为慢性乙型肝炎发展为失代偿肝硬化,经多方治疗腹水低钠血症不能纠正,改用尿素,第1日30克分三次溶于100ml水中口服,第二日增至60克分三次口服,治疗期间不限制水盐摄入。治疗5天后体重减少5公斤,血清钠由原来122mmol/L到132mmol/L,尿量每天2000～2300ml,钠水潴留表现消失。疗程中未发现不良反应,化验表明血尿素氮曾升高,但停药后即下降。作者认为间断尿素治疗主要优点是:作用迅速,给药方便;治
To a patient with urea treatment of decompensated cirrhosis of refractory ascites hyponatremia with satisfactory results. The patient was 54 years old male, originally chronic hepatitis B developed decompensated cirrhosis, after multiple treatment of ascites hyponatremia can not be corrected, the switch to urea, the first day of 30 grams in three dissolves in 100ml of water orally, the first Day 2 to 60 grams orally three times, during treatment does not limit water and salt intake. 5 days after treatment, weight loss of 5 kg, serum sodium from the original 122mmol / L to 132mmol / L, urine volume per day 2000 ~ 2300ml, sodium and water retention disappeared. No adverse reactions were found during the course of treatment. The blood urea nitrogen test showed that the blood urea nitrogen level had risen but dropped after the drug withdrawal. The author believes that the main advantages of intermittent urea treatment are: rapid action, convenient administration;