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目的了解重症监护病房(ICU)各类机械通气相关事件(VAE)的发生情况,为研究干预措施提供参考依据。方法采用前瞻性调查方法对2013年4月-7月所有新入院在ICU使用机械通气时间>2 d、年龄≥18岁的49例患者进行留置机械通气所发生的有关事件监测,并对49例患者VAE发生率进行分析比较。结果 49例患者中共发生VAE 16例,发生率为32.6%,其中包括呼吸机相关并发症3例、与感染有关的呼吸机相关并发症8例、疑诊呼吸机相关肺炎4例和拟诊呼吸机相关肺炎1例。与未发生VAE的患者相比,发生VAE的患者年龄和急性生理学及慢性健康状况Ⅱ评分更高,机械通气时间和住院时间更长,预后更差,抗菌药物使用率更高,差异均有统计学意义(P<0.05)。结论 VAE监测客观、简便,可以为患者制定VAE预防干预措施提供依据。
Objective To understand the occurrence of various types of mechanical ventilation-related events (VAE) in intensive care unit (ICU) and provide a reference for the study of intervention measures. Methods A prospective investigation was performed on all 49 newly admitted patients who underwent ICU in 49 ICU patients undergoing mechanical ventilation for> 2 days with mechanical ventilation> 2 years and ≥18 years of age from April 2013 to July 2013, The incidence of VAE were analyzed and compared. Results A total of 16 cases of VAE occurred in 49 patients (32.6%), including 3 ventilator-related complications, 8 infection-related complications, 4 suspected ventilator-associated pneumonia, Machine-related pneumonia in 1 case. Patients with VAE had higher scores for age, acute physiology and chronic health status II, longer duration of mechanical ventilation and longer hospital stay, worse prognosis, and higher rates of antimicrobial use than those who did not. Significance (P <0.05). Conclusion VAE monitoring objective and simple, can provide a basis for the development of VAE preventive interventions.