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15例慢性前列腺炎患者病程1～40年,平均12年,长期用药物治疗,包括复方新诺明和/或羧苄青霉素,均未治愈,作者用氟哌酸治疗这15位患者,每次服400mg,一日二次,共服28天为一疗程,根据病人症状,前列腺液化验及细菌培养作为判断疗效的标准,15例用药前培养都有细菌生长,13例为大肠杆菌,2例为绿脓杆菌,服氟哌酸后只有2例轻度恶心,不影响继续服药完成疗程,所有细菌对氟哌酸均敏感,治疗期间尿和前列腺液培养均转为阴性,1例1个月后失访,其余14例随访半年以上,9例(64%)痊愈,其中6例尿和前列腺液培养持续阴性达2年者1例,1年者2例,半年者3例,3例结束疗程后发生泌尿系感染,分别在6天,560天和820天,细菌培养与原来从前列腺液中培养出来的
15 patients with chronic prostatitis duration of 1 to 40 years, an average of 12 years, long-term drug treatment, including cotrimoxazole and / or carbenicillin, were not cured, the authors of norfloxacin treatment of these 15 patients, each service 400mg twice a day for a total of 28 days for a course of treatment, according to the patient’s symptoms, prostate fluid tests and bacterial culture as a criterion to determine the efficacy of 15 cases of bacterial growth before treatment, 13 cases of Escherichia coli, 2 cases Pseudomonas aeruginosa, after taking norfloxacin only 2 cases of mild nausea, does not affect the continued medication to complete the course of treatment, all the bacteria were sensitive to norfloxacin during the treatment of urine and prostatic fluid culture were turned negative, 1 case 1 month later The remaining 14 cases were followed up for more than half a year and 9 cases (64%) were cured. Among them, 6 cases of urinary and prostatic fluid culture continued negative for 2 years in 1 case, 1 case in 2 cases, 6 months in 3 cases and 3 cases in the end After urinary tract infection, respectively, at 6 days, 560 days and 820 days, bacterial culture and the original from the prostatic fluid culture out