许多年来,为了减少菌斑形成、龋病和牙周病,采用了各种疗法和不同的药物。目前已有大量的文献报道关于应用消毒剂,抗酶药物、抗菌素、菌苗以及旨在改变口腔生态学的各种方法作为防龋和减少菌斑形成的研究。消毒剂口腔细菌的计数在一天中以清晨最高,在第一餐饭后大约减少50%,然后迅速增加, For many years various treatments and different medications have been used to reduce plaque formation, caries and periodontal disease. A large body of literature has been published on the use of disinfectants, anti-enzyme drugs, antibiotics, bacterins, and various approaches aimed at altering oral ecology as anti-caries and plaque-forming studies. The counts of disinfectant oral bacteria were highest in the morning in the morning, reduced by about 50% after the first meal and then increased rapidly,