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目的总结男性乳腺癌的临床病理特点、诊断、治疗及预后。方法回顾性分析经手术治疗的9例男性乳腺癌患者的临床资料,均经病理证实诊断,占本院同期收治乳腺癌的0.2%。9例均行手术治疗;其中改良根治术7例,单纯乳腺切除术1例,乳腺肿物扩大切除术1例。术后辅以化疗、放疗和/或内分泌治疗。结果9例患者平均年龄66.0岁,以浸润性导管癌为主,腋窝淋巴结转移率57.1%,ER,PR,Her-2的阳性率分别为60.0%,100%,33.3%。8例获得随访,平均随访时间74.1个月。5年总生存率60.0%(3/5)。2例死亡,其中1例高龄患者死于脑血管意外,另1例死于肝转移,余6例术后已生存10～149个月,无局部复发病例。结论男性乳腺癌因患病率低,易延误诊治。手术治疗为主的综合治疗是本病目前有效的治疗模式。
Objective To summarize the clinicopathological features, diagnosis, treatment and prognosis of male breast cancer. Methods Retrospective analysis of 9 cases of surgical treatment of breast cancer in patients with clinical data, confirmed by pathological diagnosis, accounting for the same period in our hospital to treat breast cancer by 0.2%. All the patients underwent radical surgery. Among them, seven were modified radical mastectomy, one was simple mastectomy and one was breast enlargement and excision. Postoperative adjuvant chemotherapy, radiotherapy and / or endocrine therapy. Results The average age of 9 patients was 66.0 years old, mainly with invasive ductal carcinoma. The rate of axillary lymph node metastasis was 57.1%. The positive rates of ER, PR and Her-2 were 60.0%, 100% and 33.3% respectively. 8 cases were followed up, the average follow-up time was 74.1 months. The 5-year overall survival rate was 60.0% (3/5). Two died, of which one died of cerebrovascular accident in the elderly and the other died of liver metastases. The remaining six patients survived for 10 to 149 months without any local recurrence. Conclusion Male breast cancer due to low prevalence, easy to delay diagnosis and treatment. Comprehensive treatment of surgical treatment is the current effective treatment mode of the disease.