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目的探讨急性脑梗死(ACI)患者血清C-反应蛋白(CRP)含量的改变及其意义。方法采用比浊法检测60例ACI患者及45例正常对照者的血清CRP含量,比较不同病情、不同梗死面积ACI患者的血清CRP含量变化,对二者之间的关系进行相关性分析。结果 ACI组血清CRP水平明显高于正常对照组,ACI病情重度组、大面积梗死组血清CRP的含量明显高于病情轻度组、小面积梗死组。结论 ACI患者血清CRP含量升高,并与病情严重程度和梗死面积有关。提示其可作为判断ACI病情的血清生物学指标。
Objective To investigate the changes of serum C-reactive protein (CRP) in patients with acute cerebral infarction (ACI) and its significance. Methods Serum CRP levels were measured by turbidimetric assay in 60 patients with ACI and 45 normal controls. The changes of serum CRP levels in patients with ACI of different illnesses and different infarct sizes were compared, and the correlation between them was analyzed. Results Serum CRP level in ACI group was significantly higher than that in normal control group. Serum CRP levels in ACI severe group and large infarct group were significantly higher than those in mild and small infarction group. Conclusion Serum CRP levels in patients with ACI increased, and with the severity of the disease and infarct size. Suggesting that it can be used as a serum biological indicators to determine the condition of ACI.