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目的:考察注射用盐酸头孢替安与盐酸莫西沙星氯化钠注射液配伍的稳定性。方法:在25℃与37℃下,采用联立方程分光光度法测定头孢替安与莫西沙星配伍后的含量,并测定pH,观察外观、性状变化。结果:8h内混合液外观、pH及含量均无明显变化。结论:在25℃和37℃下,注射用盐酸头孢替安与盐酸莫西沙星氯化钠注射液8h内可以配伍使用。
Objective: To investigate the stability of compatibility of cefotiam hydrochloride for injection with moxifloxacin hydrochloride sodium chloride injection. Methods: The contents of cefotiam and moxifloxacin were determined by simultaneous equation spectrophotometry at 25 ℃ and 37 ℃, and the changes of pH and appearance were observed. Results: There was no significant change in the appearance, pH and content of the mixture within 8 hours. Conclusion: Cefotiam hydrochloride for injection and moxifloxacin hydrochloride sodium chloride injection can be used within 8h at 25 ℃ and 37 ℃.