间变性少突胶质细胞瘤、IDH突变和1p19q共缺失型,Ⅲ级(O3id)的整合诊断是一个组织-分子类型,WHO(2016)分类中通过特殊的分子改变与其他弥漫性胶质瘤区别。相比之下,大家对其细胞表型特征了解较少。该研究是集中在O3id肿瘤间和肿瘤内细胞分化谱系的异质性。基于病理学、转录组学和免疫表型研究,根据新标 Anaplastic oligodendroglioma, IDH mutation and 1p19q co-deletion type, Ⅲ grade (O3id) integration diagnosis is a tissue-molecule type, WHO (2016) classification by special molecular changes associated with other diffuse glioma the difference. In contrast, we know less about their phenotypes. The study is focused on the heterogeneity of O3id tumors and intracellular tumor cell lineage. Based on pathology, transcriptomics and immunophenotyping, according to the new standard