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目的:观察连朴饮联合四联疗法治疗幽门螺杆菌(Hp)相关性胃炎(脾胃湿热证)临床疗效。方法:113例Hp相关性胃炎(脾胃湿热证)患者,随机分为观察组和对照组,对照组57例,采用常规的西医治疗;观察组56例,在常规西医治疗的基础上加用连朴饮治疗疗程为28天。结果:不良反应发生率观察组8.93%,对照组24.56%,2组比较,差异有统计学意义(P<0.05)。Hp根除率观察组89.39%,对照组64.91%,2组比较,差异有统计学意义(P<0.05)。2组治疗后症状积分均有下降,与本组治疗前比较,差异有统计学意义(P<0.05);治疗后观察组积分下降显著低于对照组,与对照组比较,差异有统计学意义(P<0.05)。结论:连朴饮联合四联疗法治疗Hp相关性胃炎(脾胃湿热证)临床效果显著,副作用小,症状改善明显,可提高Hp根除率。
Objective: To observe the clinical efficacy of Lianpu Decoction combined with quadruple therapy in the treatment of Helicobacter pylori (Hp) -related gastritis. Methods: A total of 113 patients with Hp-related gastritis (spleen-stomach damp-heat syndrome) were randomly divided into observation group and control group. 57 cases in control group were treated with routine Western medicine. 56 cases in observation group were treated with conventional western medicine Park drink treatment for 28 days. Results: The incidence of adverse reactions was 8.93% in the observation group and 24.56% in the control group. There was significant difference between the two groups (P <0.05). Hp eradication rate was 89.39% in the observation group and 64.91% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the scores of symptom scores decreased in both groups, with statistical significance (P <0.05) before treatment; the scores of the observation group decreased significantly after treatment compared with the control group, the difference was statistically significant (P <0.05). CONCLUSION: Lianpu Decoction combined with quadruple therapy can treat Hp-related gastritis (spleen-stomach damp-heat syndrome) with obvious clinical effect, small side effects and obvious improvement of symptoms, which can improve the Hp eradication rate.