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营养性驱铅饮料对铅致骨髓细胞微核异常的防治大鼠研究结果表明:铅料组饮铅[659mg/(kg.d)]连续3月后,平均骨髓细胞微核千分率高达9.75,平均血铅高达3.69±0.05μmol/L,体重仅为216.9±24.6g。而饮料组[铅:659mg/(kg·d)+饮料]大鼠平均骨髓细胞微核千分率为5.22,与铅料组相比差异有高度显著性(P<0.01),与空白对照组(3.94‰)相近(P<0.05);平均血钳浓度(1.58±0.05μmol/L)也较铅料组低(P<0.01),而体重(278.1±73.0g)则较铅料组高(P<0.01),而与空白对照组(287.9±100.1g)相近(P>0.05)。提示:营养性驱铅饮料防治铅致骨髓细胞微核异常有明显效果,且能促进机体正常发育。
Nutritional lead-driven drink lead-induced micronucleus abnormalities in bone marrow cells in rats The results showed that: Lead group lead [659mg / (kg.d)] for 3 months, the average rate of bone marrow micronucleus rate as high as 9 .75, mean blood lead was 3.69 ± 0.05μmol / L, body weight was only 216.9 ± 24.6g. However, the mean micronucleus rate of bone marrow cells in the drinking group [Pb: 659mg / (kg · d) + drink] was 5.22, which was significantly higher than that in the lead group (P <0.01) (P <0.05); mean blood pressure (1.58 ± 0.05μmol / L) was also lower than that of lead group (P <0.01), while body weight 278.1 ± 73.0g) was higher than that of the lead group (P <0.01), but similar to that of the blank control group (287.9 ± 100.1g) (P> 0.05). Tip: Nutritional lead-driven drink lead prevention and treatment of micronuclei abnormalities in lead-induced bone marrow cells have a significant effect, and can promote the normal development of the body.