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对象与方法参加的对象男性209人,女性124人。有性病史女性则有与淋病男性性交史,尿道涂片在多形核白细胞内有革兰氏染色阴性的淋病双球菌。怀孕、胃肠病、肝炎或肾脏病伴发淋病,或对β—内酰胺类药物过敏者被除外。经治疗评价效力3～10d 者275人。被治疗的病人随机分配,单剂口服 Cefixime400mg 或800mg,或肌肉注射 Ceftri-axone 250mg。结果用 Cefixime400mg、800mg和 Ceftria0ne 250mg 各自的治愈率分别为96%、98%和98%。淋病敏感菌株(对四环素)167例患者中有164
Subjects and methods to participate in the target of 209 males and 124 females. Sex history of women have gonorrhea and male sexual intercourse history, urethral smear in polymorphonuclear leukocytes Gram-negative gonococcal. Pregnancy, gastrointestinal disease, hepatitis or kidney disease with gonorrhea, or who are allergic to β-lactam drugs were excluded. The efficacy of treatment evaluation of 3 ~ 10d 275. The patients to be treated were randomized to receive either Cefixime 400 mg or 800 mg in a single dose or Ceftri-axone 250 mg intramuscularly. Results The cure rates for Cefixime 400mg, 800mg and Ceftria0ne 250mg were 96%, 98% and 98%, respectively. 164 of 167 patients with gonorrhea-susceptible strains (tetracycline)