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目的 :建立应力性骨折实验模型 ,探讨应力性骨折发生机理。方法 :随机将 14只兔分为两组 ,运动组 10只 ,对照组 4只。运动组置于特殊的装置内进行跑跳运动。定期对动物进行放射性核素扫描 (ECT)检查。运动组于运动第 7、14、2 1、2 8、35d分别处死 1～ 2只 ,并对ECT阳性结果部位的骨骼行病理切片观察。结果 :损害部位骨组织形态学显示 ,病理损害的严重程度随训练天数的延长而加重 ;ECT变化结果与病理切片结果不尽同步 ;用ECT诊断法建立的应力性骨折模型可观察到早期的骨骼形态学改变
Objective: To establish a stress fracture experimental model to investigate the mechanism of stress fracture. Methods: 14 rabbits were randomly divided into two groups: exercise group (n = 10) and control group (n = 4). Exercise group placed in a special device to run jump exercise. Regular animal radionuclide scan (ECT) examination. The exercise group was sacrificed on the 7th, 14th, the 12th, the 8th and the 35th days respectively for 1 to 2 weeks, and the skeletal pathological sections of the ECT positive results were observed. Results: The bone histomorphology at the lesion showed that the severity of pathological injury aggravated with the prolongation of training days. The results of ECT were not in synchronicity with the results of pathological section. The stress fracture model established by ECT diagnosis showed that the early skeletal Morphological changes