七百多年前我国古书就有过斑蟊作为药物的记载.Baranger曾报道过斑蟊素等具有抗癌活性,特别对于淋巴瘤.七十年代开始,我国不少科学工作者对它进行了一系列动物试验和临床试验,证实它对于原发性肝癌的治疗有效.对肺癌、食道癌、结肠癌及乳腺癌也有一定的疗效,目前它已被应用于临床.而后又发现一系列斑蟊素的衍生物如去甲基斑蟊素(?) More than 700 years ago in our ancient books had spotted as a record of the drug.Baranger has reported cantharidin and other anti-cancer activity, especially for lymphomas.Seventies, many of our scientists conducted it A series of animal experiments and clinical trials have confirmed its efficacy in the treatment of primary liver cancer, lung cancer, esophageal cancer, colon cancer and breast cancer have a certain effect, it has been used in clinical and later found a series of cantharidin Derivatives such as desmethylcantharidin (?)