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Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV)/chitin nanocrystals(CNC) composite scaffolds were synthesized by the salt leaching and thermally induced phase separation(TIPS) technique.The scaffolds have porous structures with macro-pores(100-300 μm in diameters) and micro-pores(10μm).The surface characteristics of the scaffolds were characterized by X-ray photoelectron spectroscopy(XPS) and static water contact angle measurement,and the mechanical properties were investigated by a compression test.Human adipose-derived stem cells(hADSCs) were seeded onto the PHBV/CNC scaffolds and in vitro cell culture results showed that the composite scaffolds enhanced the hADSCs adhesion,which implies that the material may have potential application in tissue engineering.
Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) / chitin nanocrystals (CNC) composite scaffolds were synthesized by the salt leaching and thermally induced phase separation (TIPS) technique. The scaffolds have porous structures with macro- pores -300 μm in diameters) and micro-pores (10 μm). The surface characteristics of the scaffolds were characterized by X-ray photoelectron spectroscopy (XPS) and static water contact angle measurement, and the mechanical properties were investigated by a compression test. Human adipose-derived stem cells (hADSCs) were seeded onto the PHBV / CNC scaffolds and in vitro cell culture results showed that the composite scaffolds enhanced the hADSCs adhesion, which implies that the material may have potential application in tissue engineering.