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目的：探讨短期胰岛素泵强化治疗对初诊的2型糖尿病患者血糖的控制情况及影响治疗成功的相关因素。方法：对18例初诊的2型糖尿病患者进行为期2周的胰岛素泵强化治疗。分析比较治疗前、后空腹及餐后2h血糖、糖化血红蛋白、甘油三酯、体重指数的变化,并对相关因素进行分析；随访长期的血糖控制情况。结果：2周的胰岛素泵治疗可使所有患者的血糖快速、稳定下降；13例合并降脂治疗者甘油三酯明显下降；治疗前后体重指数无变化；糖化血红蛋白也有明显下降；11例患者在用胰岛素泵治疗后采用饮食控制及运动锻炼,随访超过6个月仍保持血糖正常。年龄较轻、强化期间胰岛素用量小者,则治疗成功率较高。结论：时初发2型糖尿病患者,短期胰岛素泵强化治疗可使部分患者仅通过饮食控制及运动锻炼即能获得良好的血糖控制。
Objective: To investigate the control of blood glucose in newly diagnosed type 2 diabetic patients with short-term insulin pump intensive treatment and related factors that influence the success of treatment. Methods: 18 cases of newly diagnosed type 2 diabetic patients underwent 2 weeks of intensive insulin pump therapy. The changes of fasting, postprandial blood glucose, glycosylated hemoglobin, triglyceride and body mass index were analyzed and compared before and after treatment, and the related factors were analyzed. The long-term glycemic control was followed up. Results: After 2 weeks of insulin pump therapy, the blood sugar level of all the patients decreased rapidly and steadily. Thirteen patients with combined lipid-lowering therapy significantly decreased triglyceride, unchanged body weight index before and after treatment, and significantly decreased HbA1c Insulin pump after treatment with diet control and exercise, follow-up more than 6 months still maintain normal blood sugar. Older, intensive use of insulin during the small, the treatment success rate higher. Conclusions: When patients with type 2 diabetes mellitus initially develop short-term insulin pump intensive therapy, some patients can obtain good glycemic control only through diet control and exercise training.